BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250921T141201EDT-0134VSAV9N@132.216.98.100 DTSTAMP:20250921T181201Z DESCRIPTION:Predictive coding with cortical cell types and connectivity\n\n Hannah Choi\, Georgia Tech\n Tuesday October 7\, 12-1pm\n Zoom Link: https:/ /mcgill.zoom.us/j/87078928687\n In Person: 550 Sherbrooke\, Room 189\n \n Abs tract: The brain efficiently processes sensory information by generating a n internal model of the environment\, which is continuously updated throug h prediction errors and the suppression of expected information— a process known as predictive coding. While experimental evidence supports cortical implementation of predictive coding\, it remains unclear how this process is shaped by connectivity across the cortical hierarchy\, layers\, and di verse neuronal subtypes.\n\nI will discuss recent work from my group that investigates cortical mechanisms underlying predictive coding. By construc ting a biologically grounded network model with realistic connectivity amo ng cortical cell types\, our work uncovers context-dependent functional co nnectivity that reflects the communication of predictions and prediction e rrors across the cortical circuits. Furthermore\, by mapping algorithmic c omponents of predictive coding onto neuronal subtypes\, our study generate s experimentally testable predictions about cell-type-specific responses t o expected and unexpected stimuli. We show how different computational obj ectives such as prediction error minimization\, energy efficiency\, and re ward maximization shape cell-type-specific responses to distinct forms of expectation violation\, including contextual\, absolute\, and omission nov elty. Our study thus integrates a multi-objective normative framework with a biological circuit model\, offering a unified account of how predictive coding\, energy efficiency\, and reinforcement learning map onto cell-typ e-specific mechanisms.\n DTSTART:20251007T160000Z DTEND:20251007T170000Z SUMMARY:QLS Seminar Series - Hannah Choi URL:/science/channels/event/qls-seminar-series-hannah- choi-367779 END:VEVENT END:VCALENDAR