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UID:20250625T142051EDT-36029J758M@132.216.98.100
DTSTAMP:20250625T182051Z
DESCRIPTION:'RNA stability\, the uncharted territory of gene regulation'\n
 \nHamed Najafabadi (51³Ô¹ÏÍø)\n	Tuesday November 20\, 12-1pm\n	McIn
 tyre Building\, Room 1027\n	\n	Abstract: Widespread remodelling of gene expr
 ession underlies the cellular changes in many human diseases\, including c
 ancer. In this talk\, I will focus on a mostly uncharacterized aspect of t
 hese gene expression changes: the mRNA stability. I will present new metho
 ds that enable us to directly measure the mRNA decay rate from RNA-sequenc
 ing data\, and computational models that allow us to probe the role of RNA
 -binding proteins and microRNAs in shaping the mRNA stability landscape. T
 hese models have revealed new factors that drive transcriptome remodelling
  in different cancer types\, and suggest a central role for RNA stability 
 in determining the cell function and behaviour.\n
DTSTART:20181120T170000Z
DTEND:20181120T180000Z
LOCATION:Room 1027\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1
 Y6\, 3655 promenade Sir William Osler
SUMMARY:Seminar Series in Quantitative Life Sciences and Medicine
URL:/qls/channels/event/seminar-series-quantitative-li
 fe-sciences-and-medicine-291541
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