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UID:20250508T130253EDT-9031xUrgzg@132.216.98.100
DTSTAMP:20250508T170253Z
DESCRIPTION:\nGrâce à la générosité des fiducies Killam\, Le Neuro convoque
  lors d’une série de séminaires des conférenciers d’exception dont les tra
 vaux passionnent ses chercheurs et ceux de l’Université McGill. \n\n\nPour
  assister en personne\, inscrivez-vous ici\n\nPour regarder via Vimeo\, cl
 iquez ici\n\n\nJohannes Boltze\n\nProfesseur de neurosciences\, Université
  de Warwick\, Royaume-Uni\n\nHôte: edith.hamel [at] mcgill.ca (Edith Hamel
 )\n\nAbstract: Ischemic stroke (IS) is caused by a sudden occlusion of a b
 rain-supplying artery. Stroke is frequent due to the wide representation o
 f its risk factors\, a leading cause of death and the most frequent reason
  for permanent disability in adulthood. Despite its immense medical and so
 cio-economic impact\, re-establishing cerebral blood flow by recanalizing 
 the occluded vessel is the only established therapeutic option. However\, 
 recanalization therapies are limited by narrow time therapeutic windows\, 
 the requirement of specific infrastructure\, and numerous contraindication
 s. Cerebroprotective therapies shielding neurons and glia from ischemic da
 mage would be beneficial in IS. Previous research on such approaches has b
 een futile for decades but recent preclinical and clinical developments ha
 ve caused a renaissance of cerebroprotective paradigms. The talk will brie
 fly introduce the complex pathophysiology of IS and explain difficulties t
 he field faced during the development of cerebroprotective paradigms in th
 e past. It will then introduce the novel key strategy of acute cerebroprot
 ection and will explain why chances for a therapeutic breakthrough are now
  higher than ever. The main part of the talk will provide detailed insight
 s into selected\, currently investigated cerebroprotective approaches for 
 IS by providing data from basic science and translational animal experimen
 ts. The talk will conclude by providing a brief overview of the recently e
 stablished translational research concept of multicenter preclinical trial
 s.\n
DTSTART:20241008T200000Z
DTEND:20241008T210000Z
LOCATION:de Grandpre Communications Centre\, Montreal Neurological Institut
 e\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:Killam Seminar Series: Acute Cerebroprotection in Ischemic Stroke
URL:/neuro/fr/channels/event/killam-seminar-series-acu
 te-cerebroprotection-ischemic-stroke-358371
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