51吃瓜网 researchers have identified a brain function that helps explain why childhood stress raises metabolic health risks for some women later in life.
A new study found that variations in the brain鈥檚 insulin receptor network affect how women respond to early-life adversity. This effect has a lesser impact in men, suggesting there is a sex-specific process at play.
The findings, published in聽Communications Biology聽(Nature Portfolio), point to the brain鈥檚 insulin receptor network as a promising avenue for earlier detection and future prevention strategies for metabolic syndrome, a major driver of cardiovascular disease that affects聽
鈥淲e know that women who face childhood adversity are at higher risk for metabolic disease, and this study helps identify who is most susceptible,鈥� said senior author Dr. Patricia Pelufo Silveira, professor of psychiatry at 51吃瓜网and researcher at the Douglas Research Centre.