We are thrilled to welcome Dr. Simon Thebault to the Ludmer Centre for Neuroinformatics & Mental Health as part of our Single-Cell Genomics Brain Initiative. Dr. Thebault is an assistant professor in the Department of Neurology and Neurosurgery at 51吃瓜网, and an attending physician at the Montreal Neurological Hospital-Institute. His research is deeply rooted in translational medicine, bridging the gap between patient care and laboratory discoveries.听听
Dr. Thebault鈥檚 lab will focus on neurological autoimmune diseases, particularly Multiple Sclerosis (MS). His research harnesses the power of single-cell technologies to better understand immune cell behaviour in cerebrospinal fluid (CSF) and blood, with the goal of identifying clinically actionable biomarkers. These biomarkers could help practitioners in early detection of MS, predicting disease progression, guiding treatment regiments and ultimately improving disease outcome.听听
A key theme in his work is the immune cell fingerprint of MS, using single-cell RNA sequencing and flow cytometry. He is also exploring the role of Epstein-Barr virus (EBV) in MS pathogenesis, aiming to detect EBV-infected B cells to understand their contribution to disease progression.听听
鈥淭here is a huge spectrum of disease and a lot of heterogeneity within patients. I think a lot of that immune heterogeneity can be identified. Single-cell techniques provide an unparalleled depth to characterizing immune cells in available biofluids and defining endophenotypes within MS.鈥� 鈥� Dr. Thebault.听听
Dr. Thebault is a natural fit with the Ludmer Centre鈥檚 collaborative ethos, already working closely with Stephanie Zandee, PhD, and Charles Couturier, MD, PhD. He is also developing a partnership with Sridar Narayanan, PhD, to link his research and findings with neuroimaging.听听
Please join us in welcoming Dr. Thebault to the Ludmer Centre and to The Neuro. We look forward to the exciting contributions he will bring to our growing research community!听听
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