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DESCRIPTION:\nThe Neuro Epilepsy Day 2026: Epilepsy Across Multiple Scales 
 \n\nThe Neuro Epilepsy Day will be a full-day program\, exploring epilepsy
  research and treatment across all scales: molecular\, cellular\, circuit\
 , and connectome.\n\n\nRegister Now\n\n\nCall for Abstracts\n\nWe invite u
 ndergraduate\, graduate\, and postdoctoral trainees to submit abstracts fo
 r poster presentations at The Neuro Epilepsy Day 2026. \n\nWe encourage ab
 stracts at any stage of a project’s development—from literature reviews an
 d research questions to pilot data and ongoing studies.\n\nSubmission dead
 line: March 23\, 2026\n\nSubmit Your Abstract Here\n\nSelected abstracts w
 ill be featured in the poster session\, and five outstanding posters will 
 be invited to give a short oral presentation during the program.\n\n\n\n	\n
 		Programme\n		Speakers\n		The Pierre Gloor Lecture\n		Location\n		Sponsors\n		Scienti
 fic Committee\n	\n\n	\n		Thursday\, May 28\, 2026\n\n		Preliminary Program \n\n		
 \n			\n				\n					9:15\n					\n						Arrival & Registration\n					\n				\n				\n					9:30\n					\n						Lab Tours\n\n						Neuroimag
 ing\, EEG/FMRI\, MEG\,\n					\n				\n				\n					10:45\n					\n						Welcome and Introduction\n\n						Boris B
 ernhardt\, PhD\n							Associate Professor of Neurology and Neurosurgery\n							Epileps
 y Group Leader (Research)\, The Neuro\n					\n				\n				\n					11:00\n					\n						Keynote Lectures\n\n
 						Improving Epilepsy Surgery Planning Using MR Fingerprinting\n\n						Irene Wang\
 , PhD\n							Research Director and Staff Scientist\n							Cleveland Clinic Epilepsy Ce
 nter\n\n						Networks\n\n						Seok-Jun Hong\, PhD\n							Associate Professor of Biomedical
  Engineering Department\, SKKU\n							Sungkyunkwan University - 51³Ô¹ÏÍøUniversit
 y\n\n						Surgical Perspectives\n\n						Roy William Dudley\, FRCSC\n							Assistant Profes
 sor\, Department of Pediatric Surgery\, Department of Neurology & Neurosur
 gery\n							Montreal Children's Hospital\n\n						Alexander G. Weil\, FRCSC\, FACS\n							As
 sociate Professor\, Neurosurgeon\, Researcher\, Director\n							University of Mo
 ntreal - Sainte-Justine Hospital Research Centre\n\n						Jeffery Allan Hall\, F
 RCSC\n							Assistant Professor of Neurology and Neurosurgery\n							Epilepsy Programm
 e\, Neurosurgery Clinic\, Brain Tumour Clinic\n					\n				\n				\n					1:00\n					\n						Lunch and Pos
 ter Session\n					\n				\n				\n					2:00\n					\n						Oral Presentations\n					\n				\n				\n					3:00\n					\n						Coffee Break
 \n					\n				\n				\n					3:15\n					\n						Pierre Gloor Lecture\n\n						Brain Mosaicism in Epilepsies and 
 Cortical Malformations\n							Stéphanie Baulac\, PhD\n							Research director and Grou
 p Leader\n							Inserm and Paris Brain Institute (ICM)\n					\n				\n				\n					4:15\n					\n						Discussion
  Panel\n\n						Stéphanie Baulac\, PhD\n\n						Boris Bernhardt\, PhD\n\n						Raluca Pana\,
  MD\, FRCP\, CSCN\n\n						Myriam Srour\, MDCM\, PhD\n\n						Alexander Barnett\, PhD
 \n\n						Samantha Audrain\, PhD\n\n						Sara Lariviere\, PhD \n\n						Andrea Bernasconi\,
  MD\n\n						Neda Labdon-Bernasconi\, PhD\n					\n				\n				\n					5:00\n					\n						Cocktail Reception (ons
 ite)\n					\n				\n			\n		\n	\n\n	\n		Speakers\n\n		Keynotes:\n\n		Irene Wang\n\n		Dr. Irene Wang 
 is the Research Director and Full Staff at the Cleveland Clinic Epilepsy C
 enter and an Associate Professor of Neurology at the Cleveland Clinic Lern
 er College of Medicine. Her research advances surgical treatments for MRI-
 negative epilepsy patients through innovative imaging and neurophysiology 
 techniques. As a trained biomedical engineer with a strong foundation in c
 linical neurophysiology and neuroimaging\, Dr. Wang has pioneered the inte
 gration of advanced imaging into clinical practice to enhance patient care
 . She has authored over 120 peer-reviewed papers and serves as Associate E
 ditor for Epilepsia. Dr. Wang has received continuous support from the Nat
 ional Institute of Health and serves as a charter member of the NIH Imagin
 g Technology for Neuroscience study section. Dr. Wang also chairs the MRI 
 Data Task Force of the ILAE Big Data Commission and serves on the Imaging 
 Task Force of the ILAE Diagnostic Methods Commission.\n			\n			Improving Epileps
 y Surgery Planning Using MR Fingerprinting\n			More details to come...\n\n		 \n
 \n		Stéphanie Baulac | Pierre Gloor Lecture\n\n		Stéphanie Baulac is a Researc
 h Director at Inserm and Group Leader at the Paris Brain Institute (ICM) o
 f the MOSAIC Team « Genetic Mosaicism in Epilepsy and Neurodevelopmental D
 isorders » Her team implements a comprehensive translational approach span
 ning from the identification and characterization of somatic mutations in 
 brain tissues obtained from patients undergoing epilepsy surgery to in-dep
 th functional analysis\, combining functional testing on patient-derived b
 rain organoids\, and mouse models. \n			\n			Brain Mosaicism in Epilepsies and C
 ortical Malformations\n			Focal cortical dysplasia type II (FCDII) is a corti
 cal malformation causing refractory epilepsy\, resulting from developmenta
 l somatic mutations in mTOR pathway genes. To understand how these mutatio
 ns create a mosaic pattern of affected cells and lead to cortical dyslamin
 ation\, we performed comprehensive single-nucleus analyses of surgical sam
 ples from genetically-characterized FCDII patients. By combining genotypin
 g and transcriptomics at single-cell resolution\, we revealed that mutatio
 ns predominantly affect glutamatergic neurons and astrocytes\, creating di
 stinct transcriptional programs in both mutated and non-mutated cells. Thi
 s mosaicism drives cell-type-specific dysregulation of synaptic and neurod
 evelopmental pathways that likely contribute to epileptogenesis. Notably\,
  our analysis of cytomegalic cells uncovered pronounced alterations in mit
 ochondrial metabolism pathways and cellular senescence. We uncover a signa
 ture associated with cellular senescence in abnormal FCDII cells and furth
 er provide evidence in preclinical FCDII mouse models that senolytic agent
 s could offer a novel therapeutic strategy for this disorder.\n\n		 \n\n		\n	\n
 \n	\n		The Pierre Gloor Lecture\n\n		The Pierre Gloor Lecture celebrates the li
 fe and legacy of Pierre Gloor (1923–2003)\, who joined The Neuro (Montreal
  Neurological Institute-Hospital) in 1952 as a fellow in electroencephalog
 raphy and neurophysiology. He trained under Wilder Penfield and Herbert Ja
 sper and earned his PhD from 51³Ô¹ÏÍø in 1957. Gloor collaborated
  closely with clinical and research teams at The Neuro in advancing the un
 derstanding and treatment of epilepsy\, gaining international recognition 
 for his contributions to the field.\n\n		Brain Mosaicism in Epilepsies and C
 ortical Malformations\n\n		Speaker: Stéphanie Baulac\, PhD\n			Research directo
 r and Group Leader\n			Inserm and Paris Brain Institute (ICM)\n\n		Focal cortic
 al dysplasia type II (FCDII) is a cortical malformation causing refractory
  epilepsy\, resulting from developmental somatic mutations in mTOR pathway
  genes. To understand how these mutations create a mosaic pattern of affec
 ted cells and lead to cortical dyslamination\, we performed comprehensive 
 single-nucleus analyses of surgical samples from genetically-characterized
  FCDII patients. By combining genotyping and transcriptomics at single-cel
 l resolution\, we revealed that mutations predominantly affect glutamaterg
 ic neurons and astrocytes\, creating distinct transcriptional programs in 
 both mutated and non-mutated cells. This mosaicism drives cell-type-specif
 ic dysregulation of synaptic and neurodevelopmental pathways that likely c
 ontribute to epileptogenesis. Notably\, our analysis of cytomegalic cells 
 uncovered pronounced alterations in mitochondrial metabolism pathways and 
 cellular senescence. We uncover a signature associated with cellular senes
 cence in abnormal FCDII cells and further provide evidence in preclinical 
 FCDII mouse models that senolytic agents could offer a novel therapeutic s
 trategy for this disorder.\n\n		 \n\n		\n	\n\n	\n		Location\n\n		The Montreal Neurol
 ogical Institute and Hospital is at 3801 University Street\, north of Pine
  Avenue West\, on the 51³Ô¹ÏÍø campus opposite the former Royal V
 ictoria Hospital.\n\n		Montreal is served by highway Routes 10\, 15\, 20 and
  40\, and by Greyhound Bus\, Via Rail and the P-E-Trudeau airport. In the 
 city\, bus and metro service is provided by the Société de transport de Mo
 ntréal (STM).\n\n		Wheelchair access\n\n		A wheelchair accessible entrance is 
 on University Street north of the main entrance. Another wheelchair access
 ible entrance is in the loading area behind the building: to enter the loa
 ding area\, turn into the driveway south of the main entrance. Please note
 \, there is no parking in the loading area.\n\n		Parking\n\n		Parking near the
  MNI is sometimes difficult. There are parking meters on University Street
  and a parking lot north of the main entrance. To enter the lot\, turn rig
 ht into the driveway toward Molson Stadium.\n\n		Information about parking f
 ees\n\n		Taxi Stand\n\n		There is a taxi stand on University Street across fro
 m the main entrance. You may call a cab from the free taxi phone in the ma
 in lobby near the Security Desk.\n\n		Access by Public Transportation (STM w
 ebsite)\n\n		Bus\n\n		There are four bus stops within walking distance:\n\n		\n			B
 us 144 stops at Pine Avenue and University Street\n			Bus 356 stops at Sherbr
 ooke Street and University Street (Nightbus)\n			Bus 107 stops at Pine Avenue
  and Docteur Penfield\n			Bus 24 stops at Sherbrooke Street and University St
 reet\n		\n\n		Metro\n\n		Take the Metro Green Line to the 51³Ô¹ÏÍøstation. Walk n
 orth on University Street and cross Pine Avenue. The main entrance is on t
 he right\, past the flags.\n\n		Jeanne Timmins Amphitheatre\n\n		\n			Enter the m
 ain lobby\, turn left\, and go down the hallway to the end.\n			Turn right an
 d go down the second hallway until you see another hallway on the left.\n			T
 his hallway leads to the Jeanne Timmins Foyer.\n			On your right are the Jean
 ne Timmins Amphitheatre entrance doors.\n		\n	\n\n	\n		Sponsors \n	\n\n	\n		Scientif
 ic Committee\n\n		Sam Audrain\n\n		Alexander Barnett\n\n		Boris Bernhardt\n\n		Sar
 a Larivière\n\n		Raluca Pana\n\n		Debbie Rashcovsky\n\n		Myriam Srour\n\n		 \n\n		\n
 	\n\n
DTSTART:20260528T131500Z
DTEND:20260528T210000Z
LOCATION:Jeanne Timmins Amphitheatre\, The Neuro
SUMMARY:The Neuro Epilepsy Day 2026: Epilepsy Across Multiple Scales
URL:/infect-diseases/channels/event/neuro-epilepsy-day
 -2026-epilepsy-across-multiple-scales-368975
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