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UID:20250510T131022EDT-2222u4Uku6@132.216.98.100
DTSTAMP:20250510T171022Z
DESCRIPTION:Our last seminar of the semester is coming Thursday at 2:30 in 
 Purvis 24. Lauren Maxwell will lead our discussion on the following paper 
 of her choice. Free pdf is available from this link.\n\nA Longitudinal Stu
 dy of Vaginal Douching and Bacterial Vaginosis-A Marginal Structural Model
 ing Analysis\n	\n	The etiology of bacterial vaginosis is unknown\, and there
  are no long-term therapies for preventing this frequently recurring condi
 tion. Vaginal douching has been reported to be associated with bacterial v
 aginosis in observational studies. However\, this association may be due t
 o confounding by indication-that is\, confounding by women douching in res
 ponse to vaginal symptoms associated with bacterial vaginosis. The authors
  used marginal structural modeling to estimate the causal effect of douchi
 ng on bacterial vaginosis risk while controlling for this confounding effe
 ct. In 1999-2002\, nonpregnant women (n = 3\,620) were recruited into a pr
 ospective study when they visited one of 12 public health clinics in Birmi
 ngham\, Alabama\, for routine care. Participants were assessed quarterly f
 or 1 year. Bacterial vaginosis was based on a Nugent's Gram stain score of
  7 or higher. Thirty-two percent of participants douched in every study in
 terval\, and 43.0% never douched. Of the 12\,349 study visits\, 40.2% were
  classified as involving bacterial vaginosis. The relative risk for regula
 r douching as compared with no douching was 1.21 (95% confidence interval:
  1.08\, 1.38). These findings indicate that douching confers increased ris
 k of disruption of vaginal flora. In the absence of a large randomized tri
 al\, these findings provide the best evidence to date for a risk of bacter
 ial vaginosis associated with douching.\n	\n	http://aje.oxfordjournals.org/c
 ontent/168/2/188.short\n
DTSTART:20151203T193000Z
DTEND:20151203T203000Z
LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue
  des Pins Ouest
SUMMARY:Perinatal Epidemiology Seminar/Journal Club
URL:/epi-biostat-occh/channels/event/perinatal-epidemi
 ology-seminarjournal-club-257031
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