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The fight against parasitic worms

Published: 9 April 2025

For Assistant ProfessorÌýLucienne TrittenÌýat 51³Ô¹ÏÍø, parasitic worms represent an urgent challenge and an opportunity to push the boundaries of modern science, DNA to RNA (D2R) 51³Ô¹ÏÍøwrites in a new article. With funding from D2R'sÌýFoundational ProjectsÌýprogram, Prof. Tritten is developing an innovative approach to combating parasitic infections using the gut bacteria we already have inside us.

Her project, titledÌý"Using Native Gut Bacteria to Release RNA Therapeutics Against Intestinal Nematode Infections,"Ìýaims to change how we treat infections caused by parasitic worms (also known as parasitic helminths). Parasitic helminths cause neglected tropical diseases, primarily affecting people in low-income regions with warmer climates. These worms can also affect agriculture, including animal health leading to higher food costs and economic strain on farmers. Despite their massive impact, these parasitic worms—specifically gut-dwelling worms—remain a neglected area of research.

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