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UID:20250625T220303EDT-546001XXDp@132.216.98.100
DTSTAMP:20250626T020303Z
DESCRIPTION:Dr. Alice Prince\n\nJohn M. and Yvonne T. Driscoll Professor of
  Pediatrics \; Chief\, Division of Pediatric Infectious Diseases \; Columb
 ia University \; New York\n\n \n\nTalk title: ‘’Metabolic susceptibility t
 o infection’’\n\n \n\nAbstract: Exactly what defines host susceptibility t
 o specific bacteria is not well understood. In response to infection\, CF 
 immune cells release abundant amounts of succinate and itaconate\, metabol
 ites that are substrates for Pseudomonas aeruginosa proliferation and stim
 ulate the oxidant stress that promotes biofilm formation. The availability
  of a preferred carbon source helps to explain why P. aeruginosa\, as oppo
 sed to many other opportunists\, predominate in CF.\n
DTSTART:20210112T210000Z
DTEND:20210112T220000Z
SUMMARY:CFTRc seminar
URL:/cftrc/channels/event/cftrc-seminar-328349
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