BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250514T080153EDT-8940ST8r4d@132.216.98.100 DTSTAMP:20250514T120153Z DESCRIPTION:\nThe Feindel Brain Imaging Lecture Series\n\n\n 'Network Modeli ng with Biologically-Based Cellular Models'\n\n Monday\, November 23\, 2015 at 1:00 pm\n de Grandpré Communications Centre\, Montreal Neurological Ins titute\n\n \n \n\n Dr. Frances K Skinner\n (Toronto Western Research Institute \, University Health Network\, University of Toronto)\n\n  \n\n Abstract:\n D ue to its complex dynamics and multi-scale structure\, it is an extreme ch allenge to figure out how our brains work.  Experiments alone cannot provi de an understanding – modeling and computation are essential.  Given the h igh degree of technical expertise required in experimentation\, modeling\, computation and analyses\, it is clear that to move forth in our understa nding\, open and interactive collaborations between several individuals an d disciplines are needed.\n\n Oscillatory activities are produced by severa l brain structures\, including the hippocampus\, and have been shown to be important for brain functioning.  The hippocampus is a heavily studied br ain structure due to its importance in learning and memory\, as well as be ing associated with disease states such as epilepsy and Alzheimer’s diseas e.  In this talk\, I will present some of the modeling work being done in my group to understand the essential features and mechanisms for the gener ation of rhythmic output in microcircuits of the hippocampus.  Through col laborative efforts\, we have developed and are developing cellular and net work models with tight experimental linkages\, and in which theoretical in sights and constraints can be brought to bear.  We are using them to help identify critical cellular and synaptic ‘balances’ that underlie populatio n output.  In this way\, we aim to use our models to not only understand n ormal brain functioning but also diseased states when these balances go aw ry.\n\n  \n\n Brief Bio:\n Frances Skinner studied Applied Mathematics and Co mputer Science at the University of Waterloo (B.Math) and then did graduat e studies at the University of Toronto in Biomedical Engineering (M.A.Sc.\ , Ph.D.).  She got involved in the world of Neuroscience during postdoctor al studies in Boston and California\, and has been part of the burgeoning field of Computational Neuroscience ever since.  She is interested in dete rmining neuronal and network mechanisms that contribute to brain functioni ng during normal and diseased states.  To this end\, the research in her l ab focuses on mathematical model development and usage at the interface of theory\, computation\, and experiment.\n\n  \n \n\n \n \n Unless specified oth erwise\, lectures are held on Mondays at 1:00 pm in the de Grandpré Commun ications Centre of the Montreal Neurological Institute.  \n\n To be notifie d about these lectures and all the other events going on at the BIC\, plea se join the BIC-Announcements Mailing List.  For more information\, please contact Zografos Caramanos.\n \n\n  \n\n\n \n DTSTART:20151123T180000Z DTEND:20151123T190000Z LOCATION:de Grandpré Communications Centre\, CA\, H3A 2B4\, Montreal Neurol ogical Institute and Hospital\, 3801 University Street SUMMARY:[Feindel Brain Imaging Lecture] Network Modeling with Biologically- Based Cellular Models - Dr. Frances K Skinner URL:/bic/channels/event/feindel-brain-imaging-lecture- network-modeling-biologically-based-cellular-models-dr-frances-k-255291 END:VEVENT END:VCALENDAR